Research Paper

Intermediate Syndrome Following Organophosphate Insecticide Poisoning In Emergency Department Of Eastern Nepal

Abstract :

Acute organophosphate poisoning is the most common pesticide poisoning which can be manifested in three unique phases of toxic effects e.g. Acute Cholinergic Crisis, Intermediate Syndrome (IMS), Delayed Polyneuropathy. Looking at the previous cases reports the incidence of Intermediate syndrome has been reported to be as high as 80%. The present study attempts a comparable form of incidence which was encountered in Emergency Department of BP Koirala Institute of Health Sciences (BPKIHS) in Eastern Nepal. The symptoms was analyzed with its manifestation occurred after 24 to 96 hours, affecting conscious patients without cholinergic signs, and involve the muscles of respiration, proximal limb muscles, neck flexors, and muscles innervated by motor cranial nerves. Early recognition and with appropriate supportive therapy that includes artificial respiration complete recovery may occur within or 518 days following IMS.

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