Research Study

Primary Immunodeficiency Disorders In Southern Iran

Soheila Aleyasin, Asma Erjaee, Somaye Hooshiar

Abstract :

Background: There are great diversities in the frequency of different types of Primary immunodeficiency disorders (PIDs) in between various races and geographic regions. This study was designed to gather epidemiologic information on PID patients from the Pediatric Immunologic Department and Clinic at the Shiraz University of Medical Sciences. Methods and Materials: The medical records of 60 patients with diagnosis of PID over the past 20 years, were reviewed. Results: The most common immunodeficiency disorders detected were; Combined Immunodeficiency with Associated or Syndromic Features (33.33%), Immunodeficiencies affecting cellular and humoral immunity (31.66%) and predominately antibody deficiency (23.33%). The most common specific immunodeficiency disorder severe combined immunodeficiency disorder (SCID), (30%). A consanguinity rate of 63.33% was found. Conclusion: SCID is the most common immunodeficiency disease in our geographic region with a high associated consanguinity rate. Surging the necessity for further focus on PID screening health policies in the region.

Cite This Article :

Primary Immunodeficiency Disorders in Southern Iran, Soheila Aleyasin, Asma Erjaee, Somaye Hooshiar, International Journal Of Pure Medical Research, Volume : 3, Issue : 1, January - 2018

Article :

View PDF Article No. : 1Number of Views : 621