Research Paper

Correlation Of Clinical Score And Serum Acetylcholinesterase Level, As A Predictor Of Outcome Among Patients With Acute Organophosphate Poisoning Admitted In Emergency Ward Of Tertiary Hospital In Eastern Nepal

Abstract :

Introduction: Organophosphorus (OP) insecticide self-poisoningis a major clinical and public health problem across much of rural Asia with hundreds of thousands of deaths each year.Owing to the limited availability of facilities and resource constrained settings, it is necessary to rely on clinical scores to assess the poisoning severity. Monitoring a patient's serum acetyl cholinesterase status after organophosphate poisoning enables the verification of substantial exposure to anticholinesterase agents. The present study was done to correlate serum acetylcholinesterase level with POP (Peradeniya Organophosphorus Poisoning) score with outcome among patients with acute organophosphate poisoning. Methods: A cross-sectional study was conducted amongst the patients fulfilling the inclusion criteria were included and patients were categorized according to POP scale. The study was conducted at B.P Koirala Institute of Health Sciences in the period of Jan 2016 to Dec 2016. POP score was applied and serum acetylcholinesterase level was estimated. Spearmans Rho Coefficient and Kruskal- Wallis statistical methods were applied for correlation and variables and P value of

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