Original Research Paper
A Review On The Development Of Micro Rna And Its Regulatory Role On Depression
Yizengaw Mengesha, Alemu Tebeje, Desalegn Adisu, Alemnew Tsega, Mulu Muche, Abebe Worku
Depression is a psychiatric disorder accountable for high death, morbidity, destructive health behaviors, missing occupation efficiency, and enlarged health care consumption. The presence of miRNAs in brain tissues and the potential of postmortem brain samples to recognize the severity of depressive and peripheral tissues provide a promising approach for the wide regulatory use of miRNA. Because of the inherent restrictions associated with obtaining brain tissue in vivo, the use of postmortem brain tissue may confuse by an unlimited postmortem gap and prior medication exposure. Therefore, this review aims to assess the potential broad applications of micro-RNA and its current advancement in depression.
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