Original Research Paper

To Evaluate The Relationship Of Mri Findings And Csf Analysis In Patient Diagnosed With Tuberculoma.

Abstract :

Background- CNS tuberculosis accounts for a high mortality and disability rate, representing the most severe form of tuberculosis. Early diagnosis and timely treatment are significantly critical to improve prognosis of these patients .Methods- It was a cross-sectional observational study conducted at Department of Radio-diagnosis, Geetanjali Medical College and Hospital, Udaipur. Results- MRI had a sensitivity of 87%, specificity of 92%, PPV and NPV of 83% and 94% respectively with a diagnostic accuracy of 90%. Three false negative cases were diagnosed as neurocysticercosis on MRI. One case of astrocytoma was falsely picked as tuberculoma on MRI. This patient had peripherally enhancing lesion on T1 contrast, hypointense lesion on T2, infratentorial lesion with perilesional edema.Conclusion- MRI and CSF analysis are used for diagnosis of CNS infection. MRI has a huge potential superiority in the diagnosis of CNS infections. MRI can provide the images in 3D planes and various oblique planes, without causing artifacts, and it has no side effect on human body as there is no ionizing radiation. CSF may provide with etiological basis of the disease, but may miss some diagnosis, as was in our study.

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