Original Research Paper
Effect Of Moringa Oleifera Leaves On Hematological Profile Of Fluorosis Affected Rats.
Pravallika Pagadala, Vinutha Shankar M S, Hemalatha A, Shashidhar Kn
Fluorosis is a metabolic disease that is endemic in nearly 25 countries with India being one of the most affected. It primarily affects the bone and the teeth. Moringa oleifera leaves are known to reduce the effect of fluorosis on various tissues. Objectives: To evaluate the effect of fluorosis on complete hemogram & peripheral blood smear of fluorosis affected rats. To evaluate the effect of Moringa olifera on complete hemogram & peripheral blood smear of fluorosis affected rats. To assess the ameliorative effect of Moringa olifera on plasma fluoride levels of fluorosis affected rats. Materials & Methods: Twenty four Sprague Dawley rats were housed two per cage in a room with 12 hours light and 12 hours dark cycle. The rats were allowed to acclimatize to the laboratory environment for about two weeks before the commencement of the study. Results: Red blood cell count and Hemoglobin percentage were significantly (p0.05) decreased in fluorosis affected rats compared to controls. Conclusion: The present study reveals that Moringa olifera leaves powder is effective in reducing the plasma fluoride content and also helps in improving the Hemoglobin percentage & Red Blood Cell count in fluorosis affected rats.
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