Original Research Paper

Evaluaion Of Antimicrobial Activity And Analgesic Acivity Of Dendrocnide Sinuata (blume)

Abstract :

Worldwide trend towards the utilization of natural plant remedies has created an enormous need for information about the properties and uses of the medicinal plant. Dendrocnide sinuata (Blume) is an evergreen large shrub to small trees, 37meter tall; stems and branch lets are densely covered with stinging hairs. Results of proximate analysis of dried leaves of Dendrocnide sinuata (Blume) revealed that the plant extract has low moisture content (8.5%) and a high ash value (5.46%). It also contains moderate concentration of protein (4.07%) and low concentration of fat (1.23%). As part of the investigation on the mechanism of the Analgesic activity was studied. It was effective in acetic acid induced writhing method. The different concentration of the extract were being made for anti microbial activity. It showed inhibition of gram positive and gram negative bacteria at the highest concentration 150 g/ml. Phytochemical screening of the extract of Dendrocnide sinuata (Blume) showed the presence of various phytochemical constituents alkaloids, flavanoids, triterpenes, saponin, cardiac gylycosides, resins and tannins

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