Original Research Paper

ONDANSETRON VERSUS LOW DOSE KETAMINE IN SUBARACHNOID BLOCK INDUCED HYPOTENSION AND SHIVERING - WHICH IS BETTER?

Dr Aslam. K. A, Dr. Chandra Sekhar. T, Dr. Rajay Raghunath


Abstract :

Back ground: subarachnoid block (SAB) is a safe anesthestic technique commonly practiced in world wide. However it is associated with hypotension (33%), bradycardia (13%) and shivering whish are due to hypovolemia, sympathetic blockde and Bezold- zarisch reflexthrough intracardiac serotonin (5HT3) receptors and vagus nerve.Objective: The aim of the study was to evaluate the efficacy of Ondansetron versus low dose Ketamine in prevention of hypotension and shivering during subarachnoid block.Methods: 120 patients scheduled for elective surgeries were randomly allocated in to two groups. 5 min before induction of subrachnoid block group O (n=60) received 4 mg of Ondansetron and group K (n-60) received 0.25 mg/kg Ketamine intravenously. HR, MAP,shivering , bromage scale and sedation were assessed every 5 min after SAB.Results: decreases in HR significantly lower in group K than in group O after SAB, 2, 8, 15, 25 and 40 min (P 0.001). Decrease in MAP was significantly lower in group K than in group O. Conclusion: Administration of intravenous ondansetron and ketamine prior to SAB prevents the drop in heart rate,MAP, and also prevents intraoperative shivering effectively.

Keywords :

Ondansetron   ketamine   hypotension   shivering.  

Cite This Article :

ONDANSETRON VERSUS LOW DOSE KETAMINE IN SUBARACHNOID BLOCK INDUCED HYPOTENSION AND SHIVERING - WHICH IS BETTER?, Dr Aslam.K.A, Dr.CHANDRA SEKHAR.T, Dr.RAJAY RAGHUNATH, INTERNATIONAL JOURNAL OF ADVANCED MEDICINE : Volume-5 | Issue-9 | September-2020


Article :

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