Original Research Paper

Schiff Base Ligand Synthesized From Antibiotic Cefuroxime And Salicyldehyde; Characterization And Discussion The Antimicrobial Potentials Of It.

Farhana Hoque, Tanjina Akter Anni

Abstract :

Schiff base ligand N-salicylcefuroxime was synthesized from cefuroxime and salicyldehyde to develop a more effective antibiotic. Bacterial infections have been a major health problem and the emergence of multi drug resistant complicates the situation. In the purpose of discovering more effective procurement, several antibiotics have been procured or synthesized. Advanced research of synthetic chemistry has pointed out several organic compounds with antimicrobial potentials, Schiff bases are one of such compounds. Cefuroxime is a bactericidal antibiotic. This research aimed to discuss the synthesis of a new schiff base from common antibiotic cefuroxime and salicyldehyde. This ligand synthesized and characterized by elemental analysis and some other physicochemical techniques. This synthesized compound was also characterized by different spectroscopic techniques. It was subjected to melting point determination, TLC (thin layer chromatography) determination, chemical tests, solubility test, etc. The synthesized schiff base was found more anti-bacterial potential than cefuroxime; in future it may be used as an antibiotic.

Cite This Article :

SCHIFF BASE LIGAND SYNTHESIZED FROM ANTIBIOTIC CEFUROXIME AND SALICYLDEHYDE; CHARACTERIZATION AND DISCUSSION THE ANTIMICROBIAL POTENTIALS OF IT., Farhana Hoque, Tanjina Akter Anni, INTERNATIONAL JOURNAL OF PURE MEDICAL RESEARCH : Volume-5 | Issue-2 | February-2020

Article :

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