CLINICOPATHOLOGICAL CORRELATION OF CT AND HISTOPATHOLOGY OF RETROPERITONEAL LYMPH NODE DISSECTION FOR CARCINOMA OVARY PATIENTS:A SINGLE CENTER RETROSPECTIVE STUDY
Dr. Ahmed Pervez, Dr. Naveen Thimiri Mallikarjun, Dr. Asha Reddy, Dr. Cunnigaiper Dhanasekar Narayanan
BACKGROUND: Ovarian cancer account for a large portion of female genital cancer and most of these ovarian cancers are now detected in the early stages. Importance is now placed on less radical surgeries and the exact role of RPLNDs is yet to be defined. The aim of the study is to analyse the clinicopathological status of patients who underwent retroperitoneal lymphnode dissection(RPLND) for carcinoma ovary and to compare the size of the node on imaging (CT abdomen) with node positivity on HPE. This is the first such study correlating CT findings of lymph node with pathological lympho-vascular invasion in RPLNDs done for carcinoma ovary from India verified by literature search on pubmed and NCBI.METHODS: A retrospective study of all patients who underwent RPLND diagnosed with ovarian cancer in our hospital over a period of 5 years (2011-15) were analysed. Various histopathological patterns were also evaluated. RESULTS: Forty one patients diagnosed with ovarian cancer who underwent RPLND were evaluated. The average age of the study population was 49 years. The average tumor size was 9 cm. On analysis of para-aortic node size on imaging (CT abdomen) with node positivity on HPE, a size criterion of 14mm or more was associated with node positivity. On analysis of correlation between size of the tumor and size of para-aortic node to para-aortic node positivity on HPE were both insignificant. There is correlation between size of the tumor to lymphovascular invasion on HPE.CONCLUSION: This study shows that the primary tumor size and para-aortic lymph node size can predict or suggest lymphovascular invasion and a para-aortic node size criterion of 14mm or more on CT can predict node positivity.
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