Immunity to Measles, Rubella and Hepatitis B Viruses among Iranian medical students in 2014; A cross sectional study
Background: Measles, Rubella and Hepatitis B are vaccine-preventable infectious diseases that cause several complications and impose a burden on the health systems worldwide. Medical students are exposed to these viruses in their clinical training years and thus are more susceptible to become infected. Therefore, it is rational to assess their immunity against these three viruses. Materials and Methods: In this cross sectional study in 2013, 75 blood samples were collected from medical students of Shiraz University of Medical Sciences. The population under study included 53 females and 22 males with the mean age of 22 years. IgG level against Measles, Hepatitis B and Rubella was measured by ELISA method. Results: Protective levels of IgG against Measles, Rubella and Hepatitis B were detected in 88%, 97.3% and 94.7% of the students, respectively. There was no significant correlation between gender and immunity against these viruses. We found a significant correlation between positive history of Measles and Hepatitis B vaccination and protection against these two viruses (p value: 0/016 and 0/000 respectively). A significant correlation was detected between the number of hepatitis B vaccination doses and immunity against this virus (p value: 0/016). Discussion and Conclusion: Immunity of medical students against Measles, Hepatitis B and Rubella is at an acceptable rate, However, it is prudent to address any possible problems in Measles vaccines. It is recommended that health planners evaluate the medical students regarding their immunity to these viruses before they enter their clinical training in hospitals.
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